Administer hepatitis A vaccine to all children at age 1 year (i.e., 12 to 23 months), with catch-up vaccination of unvaccinated children.
Administer hepatitis A vaccine or immunoglobulin to persons traveling to endemic areas of the world.
Administer hepatitis A vaccine to persons at increased risk for hepatitis A:
Household members and other close personal contacts (e.g., regular babysitters) of adopted children newly arriving from countries with high or intermediate hepatitis A endemicity
Men who have sex with men
Illicit drug users
Persons who regularly receive clotting-factor concentrates
Persons who have occupational risks for HAV, such as laboratory workers who work with HAV and persons who work with nonhuman primates
Administer hepatitis A vaccine to persons with chronic liver diseases.
Confirm the diagnosis of hepatitis A by testing for anti-HAV IgM.
Hospitalize persons with severe dehydration or those with signs of severe disease or liver failure, including elevated prothrombin time, encephalopathy, or hepatorenal syndrome.
Recommend adequate hydration, avoidance of alcohol, and careful attention to personal hygiene and hand washing in patients with hepatitis A.
Consult a hepatologist (or gastroenterologist) and possibly a liver transplant surgeon for patients with elevated prothrombin time or mental-status changes suggesting worsening liver failure and possible need for transplantation.